Binding energy between an enzyme and a substrate contributes to catalysis in which way?
A.
Binding energy provides the enzyme specificity for the substrate.
B.
Binding energy contributions allow for entropy reduction in the substrate-enzyme complex.
C.
Binding energy compensates for energy changes as a result of desolvation of the substrate.
D.
Binding energy contributes to the process of induced fit between the substrate and the enzyme.
E.
All of the answers are correct.