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【多选题】
以下哪些是噻嗪类利尿剂作为降压药的特征（）
A.
降压作用明确，小剂量适用于1-2级高血压或脑卒中二级预防，也是难治性高血压的基础药物之一，老年高血压、心力衰竭患者有益。
B.
可与ACEI或ARB、钙拮抗剂合用。
C.
小剂量噻嗪类利尿剂基本不影响糖脂代谢，大剂量利尿剂对血钾、血尿酸及糖代谢可能有一定影响，要注意定期检查血钾、血糖及血尿酸。
D.
痛风为禁忌证。
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brings in
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owes..... to
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