在被水饱和的天然气中加入抑制剂，吸收部分水蒸气，并将其转移至抑制剂的水溶液中。天然气中水蒸气分压低于水合物的蒸气压之后，就不会形成水合物。通常采用的水合物抑制剂（又称防冻剂）有甲醇（CH3OH）、醇（C2H6O2）、二甘醇（C5H10O3）和三甘醇（ C6H14O4 ）等，也有用氯化钙（CaCl2）的。An inhibitor is added to the water-saturated natural gas to absorb some of the water vapor and transfer it to an aqueous solution of the inhibitor. When water vapor in natural gas is lower than the vapor pressure of hydrate, it will not form hydrate. Commonly used hydrate inhibitors (also known as antifreeze) are methanol (CH3OH), glycol (C2H6O2), diethylene glycol (C5H10O3) and triethylene glycol (C6H14O4), also useful calcium chloride (CaCl2).