Passage Three Every living thing has an inner biological clock that controls behavior. The clock works all the time; even when there are no outside signs to mark the passing of time. The biological clock tells plants when to form flowers and when the flowers should open. It tells insects when to leave the protective cocoon and fly away. And it tells animals when to eat, sleep and wake. It controls body temperature, the release of some hormones and even dreams. These natural daily events are circadian rhythms. Man has known about them for thousands of years. But the first scientific observation of circadian rhythms was not made until 1729. In that year French astronomer, Jean-Jacques d “Ortous de Mairan, noted that one of his plants opened its leaves at the same time every morning, and close them at the same time every night. The plant did this even when he kept it in a dark place all the time. Later scientists wondered about circadian rhythms in humans. They learned that man’s biological clock actually keeps time with a day of a little less than 25 hours instead of 24 hours on a man-made clock. About four years ago an American doctor, Eliot Weitzman, established a laboratory to study how our biological clock works. The people in his experiments are shut off from the outside world. They are free to listen to and live by their circadian rhythms. Dr. Weitzman hopes his research will lead to effective treatments for common sleep problems and sleep disorders caused by ageing and mental illness. The laboratory is in the Monteflore Hospital in New York City. It has two living areas with three small rooms in each. The windows are covered, so no sunlight or moonlight comes in. There are no radios or television receivers. There is a control room between the living areas. It contains computers, one-way cameras and other electronic devices for observing the person in the living area. The instruments measure heartbeat, body temperature, hormones in the blood, other substances in the urine and brain waves during sleep. A doctor or medical technician is on duty in the control room 24 hours a day during an experiment. They do not work the same time each day and are not permitted to wear watches, so the person in the experiment has no idea what time it is. In the first four years of research, Dr. Weitzman and his assistant have observed 16 men between the ages of 21 and 80. The men remained in the laboratory for as long as six months. Last month, a science reporter for The New York Times newspaper, Dava Sobol, became the first woman to take part in the experiment. She entered the laboratory on June 13 th and stayed for 25 days. Miss Sobol wrote reports about the experiment during that time, which were published in the newspaper. 5 1.The biological clock is believed to play an essential role in ____