Pathway regulation can occur via the expression of tissue-specific isozymes. Glucose metabolism differs in red blood cells and liver in that red blood cells need to metabolize glucose, whereas the liver prefers to store glucose. The first step of glucose metabolism requires either glucokinase (liver) or hexokinase I (red blood cells), which are isozymes. Which one of the following best describes these different isozymes and their Km for glucose?
A.
The Km of hexokinase I is higher than the Km of glucokinase.
B.
The Km of hexokinase I is lower than the Km of glucokinase.
C.
The Km of hexokinase I is the same as the Km of glucokinase
D.
Hexokinase I is found in liver.
E.
Glucokinase is found in red blood cells.